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. 2013 Jan 24;8(1):e53190. doi: 10.1371/journal.pone.0053190

Table 2. Mutational events in ETP-ALL compared to non-ETP T-ALL.

Mutation Status ETP-ALL non-ETP T-ALL P-value
TCR rearrangement monoclonal 28 (41%) 66 (79%) <.001
n = 153 polyclonal 40 (59%) 18 (21%)
NOTCH1 mut 10 (15%) 35 (41%) <.001
n = 151 wt 56 (85%) 50 (59%)
FLT3 total mut 24 (35%) 1 (1%) <.001
n = 153 wt 44 (65%) 84 (99%)
FLT3 ITD mut 15 (22%) 0 (0%) <.001
wt 53 (78%) 85 (100%)
FLT3 D835 mut 9 (13%) 1 (1%) .003
wt 59 (87%) 84 (99%)

P values were calculated by Pearson's Chi-square test and Fisher's exact test, respectively.