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. 2013 Jan 24;8(1):e53190. doi: 10.1371/journal.pone.0053190

Table 4. Molecular characteristics of FLT3mut ETP-ALL versus FLT3wt ETP-ALL patients.

A Expression FLT3mut (n = 24) FLT3wt (n = 44) P-value
WT1 median (range) 0.78 (0.2–4.2) 0.36 (0.0–3.4) .003
IGFBP7 median (range) 0.30 (0.02–4.0) 2.52 (0.1–9.9) <.001
GATA3 median (range) 0.06 (0.0–5.7) 5.82 (0.0–6.7) <.001
BAALC median (range) 0.44 (0.01–17.7) 0.95 (0.0–27.1) .41
ERG median (range) 0.94 (0.2–18.6) 1.56 (0.0–4.2) .16
MN1 median (range) 6.35 (0.3–16.8) 7.42 (0.0–33.1) .29
BCL11B median (range) 0.20 (0.0–1.4) 0.05 (0.0–1.0) .09
MEF2C median (range) 0.71 (0.02–2.2) 0.46 (0.0–5.1) .22
B Mutation Status
NOTCH1 mut 0 (0%) 10 (23%) .01
wt 24 (100%) 34 (77%)
TCR status monoclonal 5 (21%) 23 (52%) .01
polyclonal 19 (79%) 21(48%)

A: P-values were calculated by Mann-Whitney-U-test.

B: P-values were calculated by Pearson's Chi-square test and Fisher's exact test, respectively.