Table 1. Baseline demographic characteristics of patients.
D4T+3TC+NVP (n = 360) | AZT+3TC+NVP (n = 172) | All patients (n = 532) | |
Gender - n (%) | |||
Male | 265 (73.61) | 132 (76.74) | 397 (74.62) |
Female | 95 (26.39) | 40 (23.26) | 135 (25.38) |
Age (yrs) - median (IQR) | 37 (30, 46) | 37 (30, 44) | 37 (30, 45) |
Duration of illness (months) - median (IQR) | 21.3(18.27,29.66) | 21.3(18.27,31.43) | 21.3(18.27,30.43) |
Route of transmission - n (%) | |||
Homosexual | 136 (37.78) | 72 (41.86) | 208 (39.10) |
Heterosexual | 150 (41.67) | 71 (41.28) | 221 (41.54) |
Blood | 36 (10.00) | 15 (8.72) | 51 (9.59) |
Others | 38 (10.56) | 14 (8.14) | 52 (9.77) |
Body mass index (Kg/m2) - mean±SD | 21.57±3.01 | 20.97±2.60 | 21.37±2.89 |
ALT level (U/L) - median (IQR) | 24 (17, 35) | 22.5 (16, 40) | 23 (17, 36) |
AST level (U/L) - median (IQR) | 25 (21, 33) | 25 (21, 35) | 25 (21, 34) |
Hepatitis B coinfection -n (%) | |||
positive | 50 (13.89) | 24 (13.95) | 74 (13.91) |
negative | 303 (84.16) | 145 (84.30) | 448 (84.21) |
unknown | 7(1.94) | 3(1.74) | 10(1.88) |
Hepatitis C coinfection -n (%) | |||
positive | 47 (13.06) | 17 (9.88) | 64 (12.03) |
negative | 305 (84.72) | 149 (86.63) | 454 (85.34) |
unknown - n (%) | 8(2.22) | 6(3.49) | 14(2.63) |
CD4 cell counts (cells/mm3) - mean±SD | 172±98 | 174±105 | 173±100 |
HIV-1 RNA level (log10 copies) - mean±SD | 4.52±0.74 | 4.56±0.78 | 4.53±0.75 |
ALT: alanine aminotransferase.
AST: aspartate aminotransferase.
ULN: upper limits of normal.
The presence of hepatitis B (HBV) or hepatitis C (HCV) was determined by the identified of HBV surface antigen or HCV antibodies.