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. 2013 Jan 24;8(1):e51460. doi: 10.1371/journal.pone.0051460

Figure 1. Danish surveillance system of pediatric invasive pneumococcal disease (IPD) and pneumococcal conjugate vaccine (PCV)-failures.

Figure 1

Cases of IPD caused by a serotype included in PCV7 or one of the additional serotypes included in PCV13 are identified among all IPD cases in children <5 years in order to explore possible cases of vaccine failure. PCV7 was administered in the national childhood immunization program free of charge from October 1, 2007 to April 19, 2010 and then PCV13 was offered. CSF: Cerebrospinal fluid; NSR: National Neisseria and Streptococcus Reference Center, Statens Serum Institut: SSI, MBL: Mannose-Binding Lectin, RTI: Respiratory Tract Infections, WBC: White Blood Cells.