Table 1. Invasive Pneumococcal Disease in Children Younger than 5 years after the introduction of the Heptavalent Pneumococcal Conjugate Vaccine in Denmark.
| PCV7 serotypes | Non-Vaccinated | PCV7-vaccinated3 | Total | |
| Eligible1 | Non-eligible2 | |||
| 4 | 0 | 0 | 0 | 0 |
| 6B | 9 | 2 | 0 | 11 |
| 9V | 2 | 0 | 0 | 2 |
| 14 | 7 | 2 | 4 | 13 |
| 18C | 0 | 6 | 1 | 7 |
| 19F | 1 | 3 | 3 | 7 |
| 23F | 0 | 3 | 2 | 5 |
| all | 19 (42%) | 16 (36%) | 10 (22%) | 45 (100%) |
| Additional serotypes in PCV13 | ||||
| 1 | 1 | 12 | 12 | 25 |
| 3 | 2 | 1 | 2 | 5 |
| 5 | 0 | 0 | 1 | 1 |
| 6A | 3 | 2 | 5 | 10 |
| 7F | 2 | 15 | 29 | 46 |
| 19A | 2 | 2 | 14 | 18 |
| all | 10 (10%) | 32 (30%) | 63 (60%) | 105 (100%) |
| Other serotypes 4 | 16 (42%) | 0 | 22 (58%) | 38 (100%) |
| PCR | 2 (67%) | 1 (33%) | 0 | 3 (100%) |
| Total | 47 | 49 | 95 | 191 |
1
Eligible: child within the age group targeted for primary PCV7/PCV13 vaccination or catch-up program who presented an IPD episode before vaccination.
2
Not-eligible: child outside the age group targeted for primary PCV7/PCV13 vaccination or catch-up program with PCV7.
3
PCV7-vaccinated: children who presented an IPD episode after PCV7 immunization, regardless of the number of doses received, the time of onset of illness after vaccination and the age of immunization.
4
Other serotypes: 6C, 8, 10B, 12F, 15B/C, 16F, 18F, 22F, 23F, 24F, 33F, 35B, 35F. No clear predominance of any serotype was observed. None of the patients presenting IPD due to PCV7 or PCV13 serotypes were vaccinated with PCV13.