Table 3. IgG antibody concentrations and opsonophagocytic activity with type-specific polysaccharide in a child with PCV7-failure.

Serotype	ELISA (µg/ml)	Opsonophagocytic activity (GMT)	% inhibition*
4	4.098	2697	>90
6B	6.470	2288	>90
9V	3.368	2776	>90
14	6.304	1532	>90
18C	2.327	1091	>90
19F	5.993	3767	>90
23F	0.062	482	NR

The child presented with meningitis caused by serotype 23F after receiving 2 doses of PCV7. A serotype specific antibody value of 0.35 µg/mL was considered protective.

^*Percent inhibition of opsonophagocytic activity after addition of type-specific polysaccharide. NR: no result given incomplete (poor) killing of the sample.