Table 1.
Comparison of patient characteristics according to B-mode ultrasound-based classification
Type 1 (n = 29) | Type 2b (n = 43) | Type 2c (n = 16) | P value | |
Age (yr) | 66.4 ± 9.5 | 66.9 ± 8.7 | 69.3 ± 6.8 | 0.554 |
Gender (male/female) | 23/6 | 25/18 | 8/8 | 0.085 |
HCV (positive/negative) | 28/1 | 36/7 | 14/2 | 0.241 |
Number of tumors | 1.2 ± 0.4 | 1.2 ± 0.5 | 1.6 ± 0.7 | 0.046 |
Size of tumor (mm) | 22.5 ± 3.8 | 19.0 ± 5.2 | 23.1 ± 5.6 | 0.003 |
Child-Pugh classification (A/B) | 16/13 | 31/12 | 9/7 | 0.272 |
Tumor stage (I/II/III) | 10/15/4 | 28/13/2 | 4/7/5 | 0.006 |
Activity grade (A0, 1/2, 3) | 7/22 | 14/29 | 10/6 | 0.032 |
Fibrosis stage (F0-2/3, 4) | 8/21 | 10/33 | 7/9 | 0.298 |
AFP (ng/mL) | 124 ± 246 | 118 ± 274 | 207 ± 406 | 0.564 |
AFP-L3 (%) | 7.3 ± 17.0 | 5.8 ± 16.5 | 17.5 ± 25.5 | 0.098 |
DCP (mAU/mL) | 223 ± 489 | 210 ± 482 | 299 ± 486 | 0.817 |
Data are presented as mean ± SD or n/N. HCV: Hepatitis C virus; AFP: Alpha-fetoprotein; AFP-L3: Lens culinaris agglutinin-reactive alpha-fetoprotein; DCP: Des-gamma-carboxy prothrombin.