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. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: J Am Soc Mass Spectrom. 2012 Dec 4;24(1):30–37. doi: 10.1007/s13361-012-0506-8

Spectra illustrating gas-phase covalent modification of PAMAM G0.5, including (a) isolation of the double deprotonated PAMAM G0.5 precursor, (b) ion/ion reaction between dendrimer dianion and CMC cation (structure inset), and (c) CID of isolated ion/ion complex showing a 125 Da signature loss. The lightning bolt ( ) is used to denote the ion that has been subjected to CID.

Inline graphic — Spectra illustrating gas-phase covalent modification of PAMAM G0.5, including (a) isolation of the double deprotonated PAMAM G0.5 precursor, (b) ion/ion reaction between dendrimer dianion and CMC cation (structure inset), and (c) CID of isolated ion/ion complex showing a 125 Da signature loss. The lightning bolt ( ) is used to denote the ion that has been subjected to CID.