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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Pharm Res. 2012 Oct 23;30(2):489–501. doi: 10.1007/s11095-012-0895-1

Figure 1. Common feature pharmacophore models generated with known hCAR modulators.

Figure 1

The cyan, magenta, green, and orange spheres indicate hydrophobic, hydrophobic-aromatic, hydrogen-bond acceptor, and ring-aromatic features. The structures in the figures are compounds that had the best fit values to the pharmacophore models. The drug in (A) and (C) is CITCO, and the one in (B) and (D) is CAR-17.