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. 2012 Dec 11;288(4):2501–2509. doi: 10.1074/jbc.M112.419051

FIGURE 4.

FIGURE 4.

SST treatment reduced the frequency of mEPSCs, without affecting mIPSCs. A, representative mEPSC traces and average waveforms from Ctrl or SST-treated neurons. B, SST treatment did not affect the amplitude of mEPSCs (control: 15.62 ± 1.05 pA; SST: 14.73 ± 0.78 pA, p > 0.05) but significantly reduced their frequency (control: 1.28 ± 0.18 Hz; SST: 0.64 ± 0.10 Hz, p < 0.01). C and D, cumulative probability plot of mEPSC amplitudes (p > 0.05, C) and interevent intervals (p < 0.01, D). E, representative mIPSC traces and average waveforms from control and SST-treated neurons. F, SST treatment did not affect the amplitude (control: 25.67 ± 1.37 pA; SST: 23.62 ± 0.64 pA, p > 0.05) or frequency (control: 0.75 ± 0.11 Hz; SST: 0.72 ± 0.10 Hz, p > 0.05) of mIPSCs. G and H, cumulative distributions of mIPSC amplitudes (p > 0.05, G) or interevent intervals (p > 0.05, H). The results are shown as the means ± S.E. n, shown as white numbers in the bars, represents the number of neurons. **, p < 0.01.

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