Table 1.

Demographics at screen

Screen number	Age(years)/Gender	BDP (µg )	LABA (L), Nasal steroid (N), LAMA(T), Antihistamine (A)	FEV1 (%)	Residual volume (%)	Resistance at 5 Hz (R5%)	Mannitol PD10
1	50/M	1600	L	77	159	202	95.53
2	52/F	2000	L	66	456	115	30.39
6	52/M	1000	LNA	67	83	109	139.73
3	63/M	1600	LN	54	142	215	170.37
10	37 M	2000	LA	71	170	129	13.28
23	65F	1000	L	49	216	192	337.32
27	48 M	2000	L	67	130	130	192.50
31	40/M	2000	LA	44	224	213	NR
32	28/M	1000	L	64	140	214	96.94
36	43 M	2000	L	70	162	286	455.89
37	65/M	1600	–	69	147	151	129.27
38	60/M	2000	–	57	128	153	443.57
39	61/F	2000	N	48	185	142	NR
40	52/M	2000	L	63	153	200	121.69
41	52/M	2000	LN	38	188	306	NR
Mean (SD)	51 (10)	1635 (448)		58 (13)	193 (100)	184 (56)	177 (2.81)

Challenge not performed as FEV₁ < 50% predicted. BDP, beclomethasone diproprionate equivalent; LABA, long acting beta-agonist; LAMA, long acting anti-muscarinic.