1A.
Placebo | 0.005 | 0.05 | 0.5 | 2.5 | 10 | |
---|---|---|---|---|---|---|
(n = 8) | (n = 3) | (n = 3) | (n = 6) | (n = 6) | (n = 6) | |
Age (years), mean (SD) | 26 (7) | 20 (1) | 24 (1) | 29 (6) | 22 (4) | 27 (11) |
Males, n (%) | 8 (100) | 3 (100) | 3 (100) | 6 (100) | 6 (100) | 6 (100) |
BMI (kg m−2), mean (SD), | 23 (2) | 26 (3) | 22 (2) | 25 (2) | 23 (2) | 22 (2) |
White/Caucasian, n (%) | 7 (88) | 2 (67) | 2 (67) | 6 (100) | 5 (83) | 6 (100) |
Doses of GSK679586 are presented in mg kg−1. BMI, body mass index; SD, standard deviation.