. 2012 Apr 27;75(1):162–171. doi: 10.1111/j.1365-2125.2012.04312.x

Table 3.

Propylene glycol (PG) dosages when co-administered with paracetamol or phenobarbital in currently used dosages

Drug	Propylene glycol content	Dosing guideline for drug	Drug-associated daily dose propylene glycol (mg kg⁻¹ day⁻¹)	Reference
I.v. paracetamol 10 mg ml⁻¹	800 mg PG/1000 mg paracetamol	Loading dose: 20 mg kg⁻¹	40	[1]
I.v. paracetamol 10 mg ml⁻¹	800 mg PG/1000 mg paracetamol	Maintenance dose: 10 mg kg⁻¹ every 6 h	16–32	[1]
I.v. phenobarbital 200 mg ml⁻¹	700 mg PG/200 mg phenobarbital	Loading dose: 20 mg kg⁻¹ day⁻¹	70	[18]
I.v. phenobarbital 200 mg ml⁻¹	700 mg PG/200 mg phenobarbital	Maintenance dose: 5 mg kg⁻¹ day⁻¹	17.5	[18]