FIG. 7.

Presence of 4-HNE-protein adducts in neurons in human TBI. (A, B) Triple immunolabeling of human pericontusional tissue, 15 h after trauma, with DAPI, the neuronal marker NeuN, and 4-HNE-protein adducts. Note the presence of 4-HNE-protein adducts in the cytoplasm of neurons in human pericontusional tissue. Two areas (A, B) in the tissue are shown with the second (B) in higher magnification. Scale bars are 50 μm in (A) and 12.5 μm in (B). (To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars.)