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. 2013 Jan 3;9(1):94–107. doi: 10.7150/ijbs.5246

Figure 6.

Figure 6

Activation of JNK, p38 and Akt was the downstream signaling event of MyD88. HK-2 cells were transfected with MyD88 siRNA, TRIF siRNA or scramble siRNA before AGE-LDL treatment. (A) The phosphorylation level and the total protein level of p38, JNK and Akt were examined by western blot analysis. (B) Graphic representation of the ratio of phosphorylated p38, JNK and Akt to total p38, JNK or Akt. *P<0.05 versus AGE-LDL stimulated scramble siRNA trasnfected cells. Data are expressed as mean±SD of three independent experiments.