Table 5.
Relationship of Clinicopathologic factors and Overall Survival
| Parameter | Number of patients | Overall Survival (months) Median ± SE | 95% CI | P value* (univariate) | P value (multivariate) |
|---|---|---|---|---|---|
| Age | |||||
| > 65 years | 25 | 85.2 ± 11.7 | 62.2 – 108.7 | 0.04 | 0.023 |
| ≤ 65 years | 18 | 59.7 ± 9.5 | 41.1 – 78.2 | ||
|
| |||||
| FIGO stage | |||||
| 1 and II | 26 | 90.2 ± 7.4 | 75.6 – 104.7 | 0.003 | 0.022 |
| III and IV | 17 | 32.6 ± 6.7 | 19.9 – 45.3 | ||
|
| |||||
| Architectural pattern In >50% of tumor | |||||
| Glandular | 17 | 71.6 ± 10.2 | 51.5 – 91.7 | NS | NS |
| papillary | 12 | 76.6 ± 13.6 | 49.8 – 103.3 | ||
| Solid | 10 | 36 ± 4.33 | 27.5 – 44.5 | ||
| cystic | 4 | 52.4 ± 15.5 | 22.1 – 82.6 | ||
|
| |||||
| Lymph nodes | |||||
| positive | 8 | 29.3 ± 5.4 | 18.7- 39.8 | NS | NS |
| negative | 29 | 85.3± 8.3 | 96.1- 101.4 | ||
|
| |||||
| Distant Metastases | |||||
| positive | 8 | 17.4 ± 2.4 | 12.7 – 22.1 | 0.003 | NS |
| negative | 35 | 82.5 ± 7.8 | 67.2 – 97.8 | ||
|
| |||||
| Lymphovascular Invasion | |||||
| positive | 20 | 69.9 ± 11.1 | 48- 91.7 | NS | NS |
| negative | 22 | 77.9 ± 9.5 | 59.2-96.6 | ||
|
| |||||
| Myometrium invasion | |||||
| >30% | 24 | 49.9 ± 10.5 | 29.4 – 70.5 | 0.01 | NS |
| ≤30% | 19 | 94.2 ± 6.6 | 81.1 – 107.2 | ||
|
| |||||
| Any Relapse | |||||
| positive | 11 | 42.5 ± 7.3 | 28.1 – 56.9 | 0.07 | NS |
| negative | 32 | 78.4 ± 8.4 | 61.9 - 94.7 | ||
|
| |||||
| Mitotic index | |||||
| >4 | 12 | 47.9 ± 12.9 | 22.8 – 73.2 | 0.014 | NS |
| ≤4 | 31 | 85.6 ± 8.6 | 68.8 – 102.4 | ||
|
| |||||
| Architectural grade** | |||||
| A+B | 24 | 82.3 ± 8.6 | 65.5 – 99.1 | 0.02 | NS |
| C | 19 | 38.7 ± 6.1 | 26.7 – 50.7 | ||
*
NS: not statistically significant (all p values between 0.05 and 0.09999 are listed for informational purposes); CI confidence interval; SE standard error; FIGO international Federation of Gynecology and Obstetrics.
**
Architectural grade per Yamamoto et al criteria [21].