Table 2. FLT3 mutation status of 25 acute myeloid leukemia patients with PML/RARα MRNA.
| Case | FLT3/ITD | D835Mt | FLT3mRNA | |
|---|---|---|---|---|
| Location (nt range)* | Length (bp) | Substitution | (/GAPDH) | |
| 1 | 0.048 | |||
| 2 | 1829–1885 | 57 | 0.068 | |
| 3 | 0.066 | |||
| 4 | Tyr | 0.179 | ||
| 5 | 0.165 | |||
| 6 | 1832–1864 | 33 | 0.853 | |
| 7 | 1805–1852 | 48 | 0.101 | |
| 8 | 1805–1852 | 48 | His | 0.314 |
| 9 | Ile836Phe° | 0.028 | ||
| 10 | 0.061 | |||
| 11 | 1832–1864 | 33 | 0.782 | |
| 12 | 0.073 | |||
| 13 | 1841–1861 | 21 | Tyr | 0.274 |
| 14 | Glu | 0.270 | ||
| 15 | 1800–1855 | 56+1 | 0.438 | |
| 16 | Tyr | 0.031 | ||
| 17 | 0.155 | |||
| 18 | 1829–1885 | 57 | 0.291 | |
| 19 | 1841–1861 | 21 | 0.496 | |
| 20 | Val | 0.018 | ||
| 21 | His | 0.584 | ||
| 22 | 0.076 | |||
| 23 | 0.279 | |||
| 24 | 0.005 | |||
| 25 | His | 0.128 | ||
nt, nucleotide;
the amino acid Ile of I836 was replaced with Phe.