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. 2012 Oct 16;4(4):e22. doi: 10.4081/hr.2012.e22

Table 2. FLT3 mutation status of 25 acute myeloid leukemia patients with PML/RARα MRNA.

Case FLT3/ITD D835Mt FLT3mRNA
Location (nt range)* Length (bp) Substitution (/GAPDH)
1 0.048
2 1829–1885 57 0.068
3 0.066
4 Tyr 0.179
5 0.165
6 1832–1864 33 0.853
7 1805–1852 48 0.101
8 1805–1852 48 His 0.314
9 Ile836Phe° 0.028
10 0.061
11 1832–1864 33 0.782
12 0.073
13 1841–1861 21 Tyr 0.274
14 Glu 0.270
15 1800–1855 56+1 0.438
16 Tyr 0.031
17 0.155
18 1829–1885 57 0.291
19 1841–1861 21 0.496
20 Val 0.018
21 His 0.584
22 0.076
23 0.279
24 0.005
25 His 0.128
*

nt, nucleotide;

°

the amino acid Ile of I836 was replaced with Phe.