Table 2. Cytogenetic and molecular test results of the chronic myeloid leukemia patients.
| Cytogenetic and molecular results | |
|---|---|
| Cytogenetics analysis (Bone marrow) | |
| t(9;22)(q34;q11) only | 27 (67.5) |
| Additional chromosomal abnormalities | 13 (32.5) |
| Mutation at BCR-ABL gene | |
| Absent | 27 (67.5) |
| Present | 13 (32.5) |
| Type of BCR-ABL TKD | |
| T315I | 8 (61.5) |
| E255K | 2 (15.4) |
| M351T | 1 (7.7) |
| Y253H | 1 (7.7) |
| V289F | 1 (7.7) |
| Occurrence of mutation | |
| Primary resistance | 12 (92.3) |
| Secondary resistance | 1 (7.7) |
| BCR-ABL gene fusion transcript | |
| B3a2 | 31 (77.5) |
| B2a2 | 7 (17.5) |
| Ela2 | 2 (5.0) |