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. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: J Neurooncol. 2012 Nov 27;111(2):133–143. doi: 10.1007/s11060-012-1006-1

Fig. 3 — Changes in cerebral vascular volume in mice as a function of brain tumor development. Mice at different stages of brain tumor development were given i.v. injections of radiolabelled mannitol. The brains were removed and separated into right (tumor-bearing) and left (non-tumor bearing) hemispheres and capillary depletion was performed. Vascular volume was assessed based on radioactivity (Panel A) and protein content (Panel B) of the capillary pellet. Values represent the mean ± SEM of 6 mice. * p < 0.05 compared to left hemisphere at same day as assessed using Student paired t-test.

Fig. 3 — Changes in cerebral vascular volume in mice as a function of brain tumor development. Mice at different stages of brain tumor development were given i.v. injections of radiolabelled mannitol. The brains were removed and separated into right (tumor-bearing) and left (non-tumor bearing) hemispheres and capillary depletion was performed. Vascular volume was assessed based on radioactivity (Panel A) and protein content (Panel B) of the capillary pellet. Values represent the mean ± SEM of 6 mice. * p < 0.05 compared to left hemisphere at same day as assessed using Student paired t-test.