Table 6. Stratified analysis for the six statistically significant results.
SNP | Genotype | CRC cases (n, %) | Controls (n, %) | OR (95% CI) | P |
---|---|---|---|---|---|
rs719725 | AA | 57 (60.0) | 33 (35.5) | 1.00 | |
(Female) | CA | 34 (35.8) | 53 (57.0) | 0.32 (0.17-0.61) | <0.001 |
CC | 4 (4.2) | 7 (7.5) | 0.30 (0.08-1.13) | 0.075 | |
rs4444235 | TT | 9 (10.3) | 35 (32.7) | 1.00 | |
(Female) | CT | 53 (60.9) | 45 (42.1) | 4.94 (2.11-11.56) | <0.001 |
CC | 25 (28.7) | 27 (25.2) | 3.99 (1.57-10.15) | 0.004 | |
rs3802842 | AA | 36 (25.5) | 31 (31.6) | 1.00 | |
(age ≤60 years) | CA | 69 (48.9) | 55 (56.1) | 1.05 (0.58-1.91) | 0.877 |
CC | 36 (25.5) | 12 (12.2) | 2.42 (1.06-5.52) | 0.035 | |
rs961253 | CC | 124 (81.6) | 128 (90.8) | 1.00 | |
(age ≤60 years) | AC | 28 (18.4) | 13 (9.2) | 2.29 (1.13-4.63) | 0.022 |
rs4444235 | TT | 24 (16.7) | 44 (31.2) | 1.00 | |
(age ≤60 years) | CT | 81 (56.3) | 73 (51.8) | 2.00 (1.11-3.61) | 0.022 |
CC | 39 (27.1) | 24 (17.0) | 2.95 (1.45-6.02) | 0.003 | |
rs3802842 | AA | 32 (48.5) | 31 (28.4) | 1.00 | |
(age >60 years) | CA | 25 (37.9) | 57 (52.3) | 0.44 (0.22-0.88) | 0.020 |
CC | 9 (13.6) | 21 (19.3) | 0.46 (0.18-1.19) | 0.110 |