Table 2. Relationship between expressions of OPN, α ν β3 and Pim-1 and clinicopathological parameters in NSCLC.
| Parameter | n | OPN (%) | P* | ανβ3 (%) | P* | Pim-1 (%) | P* |
|---|---|---|---|---|---|---|---|
| Sex | |||||||
| Male | 97 | 68 (70.1) | 0.496 | 75 (77.3) | 0.960 | 56 (57.7) | 0.888 |
| Female | 39 | 25 (64.1) | 30 (76.9) | 22 (56.4) | |||
| Age (year) | |||||||
| <60 | 61 | 40 (65.6) | 0.525 | 47 (77.0) | 0.969 | 36 (59.0) | 0.724 |
| ≥60 | 75 | 53 (70.7) | 58 (77.3) | 42 (56.0) | |||
| Tumor size (cm) | |||||||
| <3 | 51 | 34 (66.7) | 0.739 | 38 (74.5) | 0.562 | 28 (54.9) | 0.654 |
| ≥3 | 85 | 59 (69.4) | 67 (78.8) | 50 (58.8) | |||
| Lymph node metastasis | |||||||
| Have | 45 | 39 (86.7) | 0.001 | 43 (95.6) | 0.000 | 33 (73.3) | 0.008 |
| No | 91 | 54 (59.3) | 62 (68.1) | 45 (49.5) | |||
| Differentiation | |||||||
| Well/moderate | 88 | 51 (58.0) | 0.000 | 60 (68.2) | 0.001 | 37 (42.1) | 0.000 |
| Low | 48 | 42 (87.5) | 45 (93.8) | 41 (85.4) | |||
| Pathological typing | |||||||
| Squamous carcinoma | 40 | 26 (65.0) | 0.854 | 31 (77.5) | 0.960 | 22 (55.0) | 0.837 |
| Adenocarcinoma | 72 | 50 (69.4) | 55 (76.4) | 43 (59.7) | |||
| Other types | 24 | 17 (70.8) | 19 (79.2) | 13 (54.2) | |||
| Tumor location | |||||||
| Peripheral | 60 | 41 (68.3) | 0.991 | 46 (76.7) | 0.894 | 34 (56.7) | 0.886 |
| Central | 76 | 52 (68.4) | 59 (77.6) | 44 (57.9) | |||
| TNM stage | |||||||
| I+II | 96 | 57 (59.4) | 0.000 | 68 (70.8) | 0.006 | 47 (49.0) | 0.002 |
| III+IV | 40 | 36 (90.0) | 37 (92.5) | 31 (77.5) |
*Chi-square test