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. 2012 Sep;24(3):181–189. doi: 10.1007/s11670-012-0181-0

Table 1. Characteristics of literatures included in the meta-analysis.

SNP Author Year Country Ethnictiy Source of
controls		 Genotyping method Cancer types Case Control HWE in control (P) MAF* Power (%)**
XPC Lys939Gln rs2228001
   Kietthubthew[22] 2006 Thailand Asian Population-based PCR-RFLP OSCC 106 164 0.547 0.27 - 9.7
   Zhou[29] 2006 China Asian Population-based PCR-RFLP ESCC and GCA 580 612 0.699 0.36 - 33.3
   Ye[28] 2006 Sweden Caucasian Population-based PCR-RFLP ESCC, EA and GCA 303 472 0.540 0.38 - 22.8
   Pan[26] 2009 USA Causasian Hospital-based TaqMan Squence Detection System 7900HT EC 378 453 0.713 0.41 - 25.3
   Li[23] 2010 China Asian Hospital-based TaqMan MGB real time PCR HCC 500 507 0.507 0.34 - 28.4
   Long[25] 2010 China Asian Hospital-based TaqMan iQ5 Bio-Rad HCC 1,156 1,402 0.606 0.36 - 60.6
   Dong[19] 2008 China Asian Population-based PCR-RFLP GCA 253 612 0.699 0.36 - 21.9
   Long[24] 2010 China Asian Hospital-based PCR-RFLP GAA 361 616 0.445 0.35 - 26.4
   Hansen[21] 2007 Denmark Caucasian Population-based TaqMan Squence Detection System ABI7500 CRC 395 797 0.112 0.37 - 30.4
   Engin[20] 2010 Turkey Causasian Hospital-based PCR-RFLP CRC 110 116 0.642 0.53 - 10.0
   Wu[27] 2011 China Asian Population-based PCR-RFLP CRC 420 842 0.639 0.36 - 31.6
XPC cintron9 PAT+/-
   Casson[30] 2005 Canada Caucasian Population-based PCR-RFLP EA 56 95 0.808 0.36 6.6 -
   Wang[32] 2006 China Asian Hospital-based PCR-RFLP PC 101 337 0.564 0.36 10.0 -
   Sugimura[31] 2006 Japan Asian Hospital-based PCR-RFLP OSCC 122 241 0.131 0.40 10.6 -
   Kietthubthew[22] 2006 Thailand Asian Population-based PCR-RFLP OSCC 106 164 0.472 0.26 8.1 -
   Pan[26] 2009 USA Caucasian Hospital-based PCR-RFLP EC 379 443 0.362 0.37 19.7 -
   Dong[19] 2008 China Asian Population-based PCR-RFLP GCA 253 612 0.786 0.35 17.5 -
   Wu[27] 2011 China Asian Population-based PCR-RFLP CRC 412 832 0.689 0.35 24.5 -
XPC Ala499Val rs2228000
   Zhou[29] 2006 China Asian Population-based PCR-RFLP ESCC and GCA 580 612 0.217 0.31 24.7 -
   Pan[26] 2009 USA Caucasian Hospital-based TaqMan Squence Detection System 7900HT EC 383 450 0.133 0.24 16.3 -
   Dong[19] 2008 China Asian Population-based PCR-RFLP GCA 253 612 0.169 0.31 16.6 -
   Long[24] 2010 China Asian Hospital-based PCR-RFLP GAA 361 616 0.673 0.32 20.2 -
   Li[23] 2010 China Asian Hospital-based TaqMan MGB real time PCR HCC 500 507 0.787 0.42 24.3 -
   Wu[27] 2011 China Asian Population-based PCR-RFLP CRC 419 838 0.447 0.37 25.3 -

HWE, Hardy-weinberg equilibrium; MAF, Minor allele frequency; PAT, Poly AT; *for Lys939Gln rs2228001, MAF refers to the frequency of C allele; for Ala499Val rs2228000, it refers to frequency of T allele; for PAT, it refers to poly AT deletion; **Power was computed by the DSTPLAN4.3 software with MAF in controls as the frequency of risk factor and OR was selected with 1.20 and 1.85 as relative risk, respectively. OSCC, oral squamous cell carcinoma; ESCC, esophageal squamous cell carcinoma; GCA, gastric cardiac adenocarcinama; EC, esophageal cancer; HCC, hapatocellular carcinoma; PCR-RFLP, polymerase chain reaction fragment length polymorpaism