Table 2.
Characteristics of kidney volumes in newborns with respect to BMP4 and BMPR1A polymorphisms
| Variable | BMPR1A (A5659T, rs7922846) | paD | paR | BMP4 (T455C, rs17563) | paD | paR | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| AA (n = 82) | AT (n = 81) | TT (n = 16) | CC (n = 57) | CT (n = 93) | TT (n = 29) | |||||
| LKV (ml) | 12.8 ± 3.4 | 12.8 ± 2.9 | 14.4 ± 4.8 | 0.951 | 0.062 | 12.7 ± 3.0 | 13.0 ± 3.6 | 12.9 ± 3.4 | 0.560 | 0.951 |
| RKV (ml) | 11.7 ± 3.0 | 12.3 ± 3.0 | 13.6 ± 5.4 | 0.247 | 0.070 | 11.8 ± 2.7 | 12.1 ± 3.4 | 12.8 ± 4.0 | 0.429 | 0.247 |
| LKV/RKV | 1.1 ± 0.3 | 1.1 ± 0.2 | 1.1 ± 0.2 | 0.484 | 0.947 | 1.1 ± 0.2 | 1.1 ± 0.3 | 1.1 ± 0.3 | 0.858 | 0.484 |
| TKV (ml) | 24.4 ± 5.8 | 25.1 ± 5.1 | 28.0 ± 10.0 | 0.505 | 0.043 | 24.5 ± 5.3 | 25.1 ± 6.4 | 25.7 ± 6.6 | 0.449 | 0.505 |
| TKV/BSA (ml/m2) | 105.7 ± 23.3 | 107.8 ± 19.8 | 122.7 ± 43.8 | 0.327 | 0.013 | 106.1 ± 20.9 | 108.1 ± 25.0 | 112.3 ± 30.1 | 0.457 | 0.327 |
LKV left kidney volume, RKV right kidney volume, TKV total kidney volume, BSA body surface area
apD and pR are test probabilities with dominant (TT + AT versus AA [rs7922846], TT + CT versus CC [rs17563]) and recessive (TT versus AT + AA [rs7922846], TT versus CT + CC [rs17563]) modes of inheritance of the minor alleles, respectively