Figure 4.

CARRA Registry, selected demographics (as of February 2012, data from 53 sites), see also table 1. (A) Distribution of subject enrollment by site. The majority of registry subjects (3647 out of 6175 total subjects enrolled, or ∼60%) are found at sites enrolling <200 subjects (N=44 sites), reflecting the broad collaboration needed within this research community to achieve sufficient populations to conduct significant research investigations; (B) age at onset of disease symptoms by disease diagnosis. Upper age distribution is right-censored due to pediatric-onset inclusion criteria.