Table 3.

Demographic data.

Study	Age (mean ± SD)		Gender F:M		Periodontal history exclusions	Smoking		General health
Heitz-Mayfield et al., 2011	T/57	C/53	T/6:8	C/9:6	Untreated periodontitis, FMNS>25%	T/2	C/2	healthy
Thöne-Mühling M et al., 2010	T/46.3 ±10.1	C/53.3 ±11.3	T/2:4	C/1:4	Untreated periodontitis	T/3	C/2	healthy, no antibiotics within the last 6 month
Ramberg P. et al., 2009	T/57 ± 7	C/58 ± 8	T/20:10	C/19:10	Untreated periodontitis	not reported		healthy, no antibiotics within the last 1 month
Màximo MB et al., 2009	55.8±17		8F:4M		Untreated periodontitis	non smokers		healthy, non antibiotics within the last 6 months
Duarte PM et al., 2009	55.8±17		6F:4M		Untreated periodontitis	non smokers		healthy, no antibiotics within the last 6 month