Table 1. Recommendations for Medical Therapy and Pulmonary Endarterectomy in Patients With CTEPH (from ¹).

Recommendation	Class and Level of Evidence
Patients with objectively proven CTEPH should be promptly evaluated for pulmonary endarterectomy, even if symptoms are mild	Class I; Level of Evidence B
Patients with objectively proven CTEPH should receive indefinite therapeutic anticoagulation in the absence of contraindications	Class I; Level of Evidence C
PAH (WHO Group I)-specific medical therapy maybe considered for patients with CTEPH who are not surgical candidates (because of comorbidities or patient choice) or who have residual pulmonary hypertension after operation not amenable to repeat pulmonary endarterectomy at an experienced center	Class IIb; Level of Evidence B
PAH (WHO Group I)-specific medical therapy should not be used in lieu of pulmonary Endarterectomy or delay evaluation for pulmonary endarterectomy for patients with objectively proven CTEPH who are or may be surgical candidates at an experienced center	Class III; Level of Evidence B