Table 2.
Tests affected by floor or ceiling values
| Test | Cut-off | Placebo | Morphine | Buprenorphine | ||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Low | High | Low | High | |||
| Ceiling | ||||||
| EPTo, preburn | 100 | 1 | 1 | 2 | 2 | 2 |
| EPTo, PB1 | Units | 1 | 1 | 4 | 7 | 8 |
| EPTo, PB2 | 1 | 3 | 6 | 6 | 8 | |
| EPTo, PB3 | 1 | 3 | 6 | 5 | 8 | |
| HPT, preburn | 50°C | 4 | 4 | 5 | 6 | 3 |
| HPT, PB1 | 5 | 5 | 5 | 8 | 11 | |
| HPT, PB2 | 5 | 10 | 9 | 12 | 17 | |
| HPT, PB3 | 6 | 10 | 8 | 11 | 12 | |
| CPP | 180 sec | 0 | 1 | 2 | 1 | 3 |
| CPTo | 9 | 12 | 13 | 14 | 15 | |
| PTo1 | 1.600 g | 1 | 5 | 6 | 2 | 4 |
| PTo2 | 0 | 2 | 4 | 4 | 6 | |
| Floor | ||||||
| 2HA, PB 1 | 0 cm2 | 6 | 5 | 6 | 5 | 6 |
| 2HA, PB 2 | 6 | 5 | 5 | 7 | 6 | |
| 2HA, PB 3 | 6 | 6 | 5 | 10 | 7 | |
Notes: Number of subjects for each assessment variable reaching floor or ceiling values divided on placebo, low- and high-dose morphine and low- and high-dose buprenorphine (n = 28 in all groups, except low dose morphine, n = 27).
Abbreviations: EPTo, electrical pain threshold; HPT, heat pain threshold; CPP, cold pressor test pain threshold; CPTo, cold pressor test pain tolerance; PTo1, pressure pain tolerance (before CPT); PTo2, pressure pain tolerance (after CPT); 2HA, secondary hyperalgesia area; PBI, 1 hour postburn; PB2, 2 hours postburn; PB3, 3 hours postburn.