Fig. 4. Improved spatial learning and memory in rats treated with D-Asp.
(a) 12 rats treated with 40 mM sodium D-Asp and 12 rats treated with 40 mM NaCl (control) were trained in the Morris water maze to measure latency in reaching the platform hidden in the maze. After the acquisition phase, the platform position was changed before starting the reversal phase, while the other settings were the same. (b) Relationship between the endogenous D-Asp in 120-day old rat hippocampus and the time to reach the platform in the Morris water maze system of the corresponding rats that were trained in the Morris water maze system. Figure is adapted from (Topo et al. 2010) and used with permission, Springer Science+Business Media.