Table 2.
Adverse Drug Reactions and the suspected antihypertensive medicine
| Suspected Drugs (No. of Prescriptions) | ADRs Experienced | No. of ADRs (%*) | Interventions |
|---|---|---|---|
| Calcium Channel Blockers | |||
| Amlodipine (68) |
Ankle edema |
02 (2.94%) |
Dechallenge |
| |
Abdominal pain |
02 (2.94%) |
Symptomatic treatment |
| |
Sedation |
01 (1.47%) |
Symptomatic treatment |
| |
Pedal edema |
01 (1.47%) |
Symptomatic treatment |
| |
Back pain |
01 (1.47%) |
Symptomatic treatment |
| Total |
|
07 (10.29%) |
|
| Diuretics | |||
| Torasemide (18) |
Fatigue |
01 (5.55%) |
Symptomatic treatment |
| |
Visual impairment |
01 (5.55%) |
Dechallenge |
| |
Dizziness |
01 (5.55%) |
No change in treatment |
| Total |
|
03 (16.66%) |
|
| Amiloride (09) |
Dizziness |
01 (11.11%) |
No change in treatment |
| |
Loss of appetite |
01 (11.11%) |
Symptomatic treatment |
| Total |
|
02 (22.22%) |
|
| Grand Total |
|
05 (18.51%) |
|
| ACE Inhibitors | |||
| Ramipril (33) |
Dry cough |
02 (6.06%) |
Dechallenge |
| Total |
|
02 (6.06%) |
|
| Angiotensine Receptor Blockers | |||
| Telmisartan (17) |
Dizziness |
01 (5.88%) |
No change in treatment |
| Losartan (22) |
Dizziness |
01 (4.54%) |
No change in treatment |
| Olmesartan (06) |
Dizziness |
01 (16.66%) |
No change in treatment |
| Total |
|
03 (6.66%) |
|
| Beta-blockers | |||
| Atenolol (34) |
Bradycardia |
01 (2.94%) |
No change in treatment |
| Metoprolol (12) |
Headache |
01 (8.33%) |
No change in treatment |
| Propranolol (20) |
Insomnia |
01 (5.00%) |
Dechallenge |
| |
Depression |
01 (5.00%) |
Dechallenge |
| Total | 04 (6.06%) | ||
*The percentage of ADRs was calculated from no of prescriptions of suspected drug.