Table 1. Summary of the metabolic reconstructions employed in this study. BΘ, B. thetaiotaomicron.
Bacteroides thetaiotaomicron | Mus musculus | Integrated model | |
---|---|---|---|
Acronym |
iAH991 |
iSS1393 |
iexGFMM_BΘ |
Total reactions |
1488 |
4091 |
7239 |
Metabolic and transport reactions |
1213 |
3505 |
5443 |
Exchange and sink reactions |
275 |
585 |
Internal: 728 External: 1068 |
Compartment specific metabolites |
1152 |
2950 |
5164 |
Genes |
991 |
1393 (1778 transcripts) |
2769 |
Gene associated reactions |
1068 |
2357 |
3428 |
Reversible reactions |
45% |
n. d. |
n. d. |
Irreversible reactions |
55% |
n. d. |
n. d. |
Blocked reactions |
87 |
784 |
1219 |
Number of compartments |
2 |
8 |
12 |
Usable carbohydrates as sole carbon sources |
63 |
n. d. |
n. d. |
Growth on minimal medium (MM) |
Yes, on anaerobic glucose MM67 |
Yes, on aerobic amino acid MM supplemented with glucose, fatty acids and ions21 |
n. d. |
Oxygen requirement in silico |
no |
yes |
Mouse: yes BΘ: no |
Genes predicted to be essential on minimal medium | 204 | 54 | n.d. |