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. 2013 Jan 25;8(1):e55253. doi: 10.1371/journal.pone.0055253

Table 4. Crude and adjusted hazard ratios of hemorrhagic stroke for the migraine and non-migraine groups, stratified by sex and age.

Patient sex* Patient age
Women Men <45years Inline graphic45years
Non-MG MG Non-MG MG Non-MG MG Non-MG MG
Occurrence of HS N = 72915 N = 14583 N = 31710 N = 6342 N = 61520 N = 12304 N = 43105 N = 8621
Yes, n (%) 145 (0.20) 59 (0.40) 110 (0.35) 54 (0.85) 65 (0.11) 37 (0.30) 190 (0.44) 76 (0.88)
No, n (%) 72770 (99.80) 14524 (99.60) 31600 (99.65) 6288 (99.15) 61455 (99.89) 12267 (99.70) 42915 (99.56) 8545 (99.12)
Crude hazard ratio (95% CI) 1.00 2.04 (1.50–2.76) 1.00 2.46 (1.78–3.41) 1.00 2.85 (1.90–4.27) 1.00 2.00 (1.54–2.61)
Adjusted hazard ratio (95% CI) 1.00 1.95 (1.44–2.64) 1.00 2.38 (1.72–3.30) 1.00 2.58 (1.72–3.88) 1.00 1.91 (1.46–2.49)
*

Variables included in the multiple regression analyses were age, hypertension (with and without medication), diabetes, hyperlipidemia, coronary heart disease, chronic rheumatic heart disease, other heart disease, and the use of anticoagulant medication.

Variables included in the multiple regression analyses were sex, hypertension (with and without medication), diabetes, hyperlipidemia, coronary heart disease, chronic rheumatic heart disease, other heart disease, and the use of anticoagulant medication.

Abbreviations: HS, hemorrhagic stroke; MG, migraine group.

P<0.0001.