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. 2013 Jan 25;8(1):e55072. doi: 10.1371/journal.pone.0055072

Figure 7. Fenretinide delays tumor growth in vivo.

Figure 7

Growth rate of Rh4 xenograft tumors in NOD/Scidil2rg−/− mice (n = 3) treated with sterile 0.9% NaCl (control) or fenretinide (treated), Left: tumor volume was determined using a calliper, Right: tumor volumes determined according to luminescence values measured by IVIS Lumina XR imaging system (Caliper Life Sciences). B) Immunohistological staining of Ki67 (left) and activated caspase 3 (right) of Rh4 xenograft tumor sections treated with sterile 0.9% NaCl or fenretinide. C) Quantification of Ki67 and activated caspase 3 positive cells counted per field using Image J software in Rh4 sections of tumors treated with sterile 0.9% NaCl or fenretinide. Columns, mean; bars, s.d. *p<0,05 compared to control mice.