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. 2013 Jan 25;8(1):e55072. doi: 10.1371/journal.pone.0055072

Table 1. LOPAC small-molecule compound library screening hit list.

Compound Ratioa Description
Retinoic acid p-hydroxyanilide 4,51 Vitamin A acid analog
(±)-Quinpirole dihydrochloride 4,29 Dopamine receptor agonist
ML 10302 4,04 Serotonin receptor agonist
Propantheline bromide 3,95 Muscarinic acetylcholine receptor antagonist
N,N,N’,N’-Tetramethylazodicarboxamide 3,84 Thiol-oxidizing agent
Etoposide 3,8 Topoisomerase II inhibitor
L-162,313 3,67 Angiotensin II receptor agonist
9-cyclopentyladenine 3,43 Adenylyl cyclase inhibitor
R(−)-Isoproterenol (+)-bitartrate 3,37 Adrenoceptor agonist
BRL 50481 3,27 Phosphodiesterase 7 inhibitor
a

Ratio = Proliferation rate/Luciferase activity as compared to the non-treated RH4-AP2ß-LF cells (5 µM incubation for 24 hours).