Table 6.
Storage condition 30 ± 2°C/65 ± 5% RH |
Drug Content (%) of formulations |
||||||
---|---|---|---|---|---|---|---|
Carvedilol | 0.2% Chitosan hydrosols | 0.4% Chitosan chlorhydrate hydrosols | 0.2% chitosan solid dispersions | 0.8% chitosan chlorhydrate solid dispersions | 0.4% Chitosan Co-grinding | 0.4% Chitosan chlorhydrate Co-grinding | |
Time 0 days |
99.56 ± 1.16 |
98.77 ± 1.31 |
98.19 ± 2.13 |
99.66 ± 1.24 |
98.17 ± 1.14 |
99.46 ± 1.11 |
98.86 ± 1.15 |
Time 90 days |
99.46 ± 1.38 |
98.67 ± 1.44 |
98.09 ± 2.34 |
99.76 ± 1.32 |
98.67 ± 1.43 |
99.27 ± 1.12 |
98.66 ± 1.34 |
Time 180 days | 99.26 ± 1.10 | 98.47 ± 1.22 | 97.69 ± 2.01 | 99.16 ± 1.16 | 98.97 ± 1.25 | 99.29 ± 1.14 | 99.10 ± 1.17 |