Table 1.
Treatment schedule |
|
Uric acid |
SGOT |
SGPT |
ALK phosphate |
Total protein |
Albumin |
Creatinine |
Blood urea nitrogen |
Cholesterol |
---|---|---|---|---|---|---|---|---|---|---|
mg/dl | IU/L | IU/L | IU/L | gm/dl | gm/dl | mg/dl | mg/dl | mg/dl | ||
C |
|
5.05 ± 1.20 |
26.83 ± 2.54 |
27.67 ± 2.64 |
70.07 ± 7.20 |
6.86 ± 1.30 |
3.95 ± 1.46 |
0.93 ± 0.15 |
14.47 ± 2.84 |
148.32 ± 12.2 |
SD |
20 D |
7.23 ± 2.51 a |
49.09 ± 4.87 a |
38.67 ± 3.54 a |
97.69 ± 10.47 a |
6.87 ± 1.27 |
3.54 ± 1.34 |
1.18 ± 0.31 |
15.60 ± 2.97 |
149.25 ± 12.4 |
|
40 D |
7.83 ± 2.57 a |
61.17 ± 3.86 a |
41.33 ± 4.08 a |
105.86 ± 12.49 a |
6.53 ± 1.17 |
3.26 ± 1.29 |
1.19 ± 0.32 |
16.69 ± 2.99 |
155.37 ± 13.74 |
|
60 D |
8.46 ± 2.79 a |
73.83 ± 4.19 a |
47.17 ± 4.56 a |
115.83 ± 13.41 a |
6.42 ± 1.04 |
3.22 ± 1.27 |
1.24 ± 0.37 a |
18.90 ± 3.14 |
160.5 ± 14.12 |
G I |
20 D |
5.14 ± 1.40 |
28.33 ± 1.11 |
26.17 ± 2.65 |
71.42 ± 7.24 |
6.96 ± 1.27 |
3.91 ± 1.45 |
0.88 ± 0.15 |
12.27 ± 2.17 |
138.79 ± 10.54 |
|
40 D |
5.017 ± 1.31 |
29.08 ± 2.87 |
27.5 ± 2.64 |
68.85 ± 7.01 |
7.21 ± 1.47 |
3.85 ± 1.43 |
0.940 ± 0.13 |
10.65 ± 1.94 |
135.24 ± 9.87 |
|
60 D |
5.65 ± 1.97 |
25.5 ± 2.43 |
22.5 ± 2.14 |
60.68 ± 6.50 |
7.11 ± 1.40 |
3.81 ± 1.40 |
0.91 ± 0.12 |
12.03 ± 2.07 |
124.33 ± 8.47 a |
G II |
20 D |
5.08 ± 1.31 |
27.17 ± 2.68 |
23.0 ± 2.20 |
57.87 ± 6.40 |
7.17 ± 1.88 |
3.86 ± 1.43 |
0.96 ± 0.1.8 |
11.81 ± 1.95 |
123.88 ± 8.44 a |
|
40 D |
6.94 ± 2.46 |
24.5 ± 2.37 |
23.33 ± 2.21 |
57.92 ± 6.42 |
7.26 ± 1.44 |
3.78 ± 1.40 |
0.96 ± 0.17 |
12.65 ± 2.23 |
118.79 ± 7.97 a |
|
60 D |
5.23 ± 1.49 |
30.0 ± 3.01 |
24.5 ± 2.36 |
58.05 ± 6.14 |
7.18 ± 1.40 |
3.85 ± 1.42 |
0.99 ± 0.19 |
13.87 ± 2.54 |
115.35 ± 7.49 a |
G III |
20 D |
5.86 ± 2.10 |
22.33 ± 2.14 |
25.5 ± 2.49 |
53.82 ± 5.68 |
7.35 ± 1.50 |
3.96 ± 1.47 |
0.98 ± 0.19 |
10.44 ± 1.89 |
120.54 ± 8.40 a |
|
40 D |
5.13 ± 1.47 |
27.17 ± 2.64 |
22.17 ± 2.10 |
53.07 ± 5.61 |
7.61 ± 1.87 |
3.83 ± 1.41 |
0.95 ± 0.17 |
12.12 ± 2.09 |
115.31 ± 7.48 a |
|
60 D |
5.017 ± 1.30 |
28.83 ± 2.76 |
21.33 ± 2.08 |
54.28 ± 5.84 |
7.08 ± 1.35 |
3.98 ± 1.49 |
0.91 ± 0.13 |
10.08 ± 1.74 |
110.23 ± 7.80 a |
RG I |
30 D |
5.47 ± 1.87 |
24.67 ± 2.38 |
23.0 ± 2.24 |
59.44 ± 6.04 |
7.25 ± 1.42 |
3.883 ± 1.42 |
0.98 ± 0.19 |
11.04 ± 1.90 |
136.48 ± 10.21 |
RG II |
30 D |
4.78 ± 1.19 |
28.04 ± 2.79 |
22.17 ± 2.17 |
58.21 ± 5.91 |
7.133 ± 1.39 |
3.917 ± 1.47 |
0.95 ± 0.17 |
11.22 ± 1.92 |
138.17 ± 10.43 |
RG III | 30 D | 4.71 ± 1.13 | 30.17 ± 3.09 | 24.17 ± 2.34 | 56.44 ± 5.74 | 7.037 ± 1.24 | 3.93 ± 1.47 | 0.98 ± 0.18 | 10.04 ± 1.70 | 143.2 ± 11.51 |
Significance level: a P ≤ 0.01 compared Control.
C- Rats treated with treated with in 2.0 ml 0.5 percent CMC each day for 60 days.
G I- Rats treated with methanolic bark extract of Aegle marmelos 200 mg/rat/day/p.o.
GII- Rats treated with methanolic bark extract of Aegle marmelos 400 mg/rat/day/p.o.
GIII- Rats treated with methanolic bark extract of Aegle marmelos 600 mg/rat/day/p.o.
RG-I- Rats withdraw from treated for 30 days after 60 days treatment of methanolic bark extract of Aegle marmelos 200 mg/rat/day/p.o.
RG-II- Rats withdraw from treated for 30 days after 60 days treatment of methanolic bark extract of Aegle marmelos 400 mg/rat/day/p.o.
RG-III- Rats withdraw from treated for 30 days after 60 days treatment of methanolic bark extract of Aegle marmelos 600 mg/rat/day/p.o.