Table 2.
Effect of methanol extract of garden egg on agar induced in vivo leukocyte mobilization
| Treatment | Dose (mg/kg) | TLC (X104) | % inhibition |
Differential Leukocyte mobilization (%) |
||||
|---|---|---|---|---|---|---|---|---|
| Neutrophils | Lymphocytes | Monocytes | Eosinophils | Basophils | ||||
| Control |
|
94.51 ± 7.93 |
|
62.75 |
34.75 |
1.0 |
0.75 |
0.75 |
| Extract |
100 |
72.62 ± 11.45** |
23 ± 2.17 |
61 |
35 |
1.5 |
1.0 |
1.5 |
| 200 |
70.25 ± 12.28** |
26 ± 1.58 |
60 |
36 |
1.25 |
1.5 |
1.25 |
|
| 400 |
64.00 ± 14.78** |
32 ± 1.58 |
57 |
39 |
1.25 |
1.0 |
1.75 |
|
| Indomethacin | 50 | 56.7 5 ± 7.89*** | 40 ± 1.92 | 60.75 | 35 | 1.25 | 1. 5 | 1.5 |
Level of Significance ***= p<0.001, ** = p<0.01, * = p<0.05 Percent inhibition of migration was calculated relative to control.