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. Author manuscript; available in PMC: 2014 Jan 18.
Published in final edited form as: Oncogene. 2012 Sep 17;32(29):3461–3469. doi: 10.1038/onc.2012.426

Figure 3. p68 is required for recruitment of p53 and RNA Pol II to the p21 promoter but not to the Bax and PUMA promoters.

Figure 3

MCF-7 cells were transfected with non-specific (NS) or p68 siRNAs and treated with etoposide prior to chromatin immunoprecipitation and qPCR (SYBR Green). Untreated cells served as controls. +: cells treated with 5μM etoposide for 16 h.

Recruitment of (A) p68, (B) p53 and (C) RNA Pol II to the p21, Bax and PUMA promoters is shown as percentage relative to input DNA.

In all graphs the values shown are the averages from 3 independent experiments +/− s.e.m. and statistically significant differences (p = <0.05) are indicated.