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. Author manuscript; available in PMC: 2013 Jan 26.

Published in final edited form as: Front Biosci (Elite Ed). 2013 Jan 1;5:697–705. doi: 10.2741/e650

Effect of AT₁ receptor siRNA on AT₁ receptor protein expression (A), and prorenin-induced phosphorylation of EGF receptor at Tyr992 (B) and Tyr1068 (C), Src (D) and ERK 1/2 (E) in HEK293 cells. Bar graphs represent mean ± SE (n=4), expressed as fold change compared with vehicle-treated cells. *P<0.05 vs. vehicle-treated cells.

Effect of AT₁ receptor siRNA on AT₁ receptor protein expression (A), and prorenin-induced phosphorylation of EGF receptor at Tyr992 (B) and Tyr1068 (C), Src (D) and ERK 1/2 (E) in HEK293 cells. Bar graphs represent mean ± SE (n=4), expressed as fold change compared with vehicle-treated cells. *P<0.05 vs. vehicle-treated cells.