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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Oct 23;1833(3):468–478. doi: 10.1016/j.bbamcr.2012.10.019

Figure 7. Proposed model for the interaction of HPS1 and HPS4.

Figure 7

The results of the co-immunoprecipitation analyses (Figures 1–4 and 6) are consistent with a model where the N- and C- termini of HPS1and the N-terminal and middle region of HPS4 are involved in the interactions, leading to BLOC-3 formation. Specifically, N-termini of HPS4 and HPS1 interact with each other, and the central portion of HPS4 interacts with both the N- and the C- termini of HPS1.