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Inhibition of hiCE by Different Salvia miltiorrhiza Root Extracts.
| extract/fraction | concentration (mg/mL) | IC50 ± SE (μg/ml) | IC50 ± SE (μg/mg) | ||
|---|---|---|---|---|---|
| o-NPA | CPT-11 | o-NPA | CPT-11 | ||
| water | 41.8 | 4,080 ± 990 | ND | 97.6 ± 23 | ND |
| acetone | 1.13 | 0.16 ± 0.05 | 0.51 ± 0.12 | 0.14 ± 0.04 | 0.45 ± 0.10 |
| ethanol (56%) | 37.1 | 179 ± 16 | 41.4 ± 9.3 | 4.82 ± 0.43 | 1.12 ± 0.25 |
| acetone fraction 16 | 1a | 0.27 ± 0.02 | 0.52 ± 0.04 | 0.27 ± 0.02 | 0.52 ± 0.04 |
The dried chromatography fraction was dissolved in DMSO at 1 mg/mL.
