Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2013 Jan 26.

Published in final edited form as: Bone Marrow Transplant. 2010 Jun 14;46(3):368–371. doi: 10.1038/bmt.2010.119

a) CT scan shows numerous peripheral and pleural based nodular densities in the lung. b) PCT is characterized histologically by necrotic thromboemboli in the distal pulmonary vessels with entrapped leukocytes and amorphous material suggestive of cellular breakdown products. In samples where the cellular debris is still viable, immunohistochemistry shows mainly macrophages (i.e., cells staining for MPO and CD68). c) The cumulative incidence of relapse at three years was significantly lower in those with PCT compared to those without PCT (0% vs. 28%, p=0.02). d) The probability of LFS at three years was significantly higher in those with PCT compared to those without PCT (79% vs. 46%, p=0.03).

a) CT scan shows numerous peripheral and pleural based nodular densities in the lung. b) PCT is characterized histologically by necrotic thromboemboli in the distal pulmonary vessels with entrapped leukocytes and amorphous material suggestive of cellular breakdown products. In samples where the cellular debris is still viable, immunohistochemistry shows mainly macrophages (i.e., cells staining for MPO and CD68). c) The cumulative incidence of relapse at three years was significantly lower in those with PCT compared to those without PCT (0% vs. 28%, p=0.02). d) The probability of LFS at three years was significantly higher in those with PCT compared to those without PCT (79% vs. 46%, p=0.03).