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. Author manuscript; available in PMC: 2013 Jan 26.
Published in final edited form as: Adv Exp Med Biol. 2012;723:215–223. doi: 10.1007/978-1-4614-0631-0_29

Fig. 29.2.

Fig. 29.2

Reduction of rds in mice by siRNA delivered by rAAV to photoreceptors. Functional analysis by ERG: graphics show maximal amplitude of a-wave (A) and b-wave (B). Analysis of rds expression in the presence of siRNA 6 or 7 (C): total RNA was extracted and analyzed using real-time PCR. Transverse section of the retina showing its intact structure thought bright field (D) and a fluorescent picture of the same field (E) showing GFP expression in approximately ½ of the retina, corresponding to rAAV transduced area.