Fig. 29.4.
Co-infection of photoreceptors in vivo with siRNA 6 or 7 plus resistant rds delivered by rAAV – reposition of rds expression by its resistant version. Functional analysis by ERG: graphics show maximal amplitude of a-wave (A) and b-wave (B). Analysis by real-time PCR of total rds expression (C) and only of resistant rds with a distinct primer (D). PCR values for rds were normalized to the levels of β-actin in the same samples.