. Author manuscript; available in PMC: 2014 Mar 1.

Published in final edited form as: Biochim Biophys Acta. 2012 Aug 30;1829(3-4):265–273. doi: 10.1016/j.bbagrm.2012.08.003

Table 2.

Yeast Pol I GTFs and their ortholog, paralogs, and structural homologs

Complex	Yeast	Human	Genome¹ and PDB² Homologs
	yRrn3	hRrn3	HEAT repeats

yCF/hSL1	Rrn11	TAF1A	Tetratricopeptide repeats
	Rrn7	TAF1B	TFIIB, Brf1, Brf2, TFB, Cyclin Fold
	Rrn11	TAF1C	WD-40 repeats, HEAT repeats
	N.A.	TAF1D	Josephin domain
	N.A.	TAF12	Histone fold

yUAF/hUBF	Rrn5	N.A.	SANT domain, Histone fold
	Rrn9	N.A.	TFIIA Toa1 subunit³
	Rrn10	N.A.	No significant matches
	Uaf30	N.A.	Swi/Snf SWIB/MDM2 domain
	Histone H3	N.A.	Histone fold
	Histone H4	N.A.	Histone fold
	Hmo1	UBF	HMG Homeobox repeats

HHpred search results against S. cerevisiae and H. sapien genome databases;

HHpred search results against PDB database;

^1&2

Transcription relevant matches are listed and matches represent tentative sequence relationships that require further study;

Rrn9 matches small region of TFIIA Toa1 subunit with low probability but high protein identity; N.A. Not applicable due to absence of homology between yeast and human Pol I factors.