Table 2.
Log blood harmane concentration by group
Group | Median harmane concentration in g−10/ml | Mean ± S.D. log blood harmane concentration in g−10/ml |
---|---|---|
| ||
Controls | 2.09 | 0.33 ± 0.39 |
Sporadic ET | 2.41 | 0.35 ± 0.51 |
Familial ET | 2.90 | 0.40 ± 0.42 |
Kruskal-Wallis testdf = 2 = 1.45, p = 0.481 | ANOVA Fdf = 2 = 0.56, p = 0.582 |
For comparison of familial ET vs. controls, Mann Whitney z = 1.26, p = 0.21.
For comparison of familial ET vs. controls, t = 1.13, p = 0.26.
In an unadjusted logistic regression analysis, log blood harmane concentration was not significantly associated with the outcome (familial ET vs. control) (OR = 1.56, 95% CI = 0.72 –3.36, p = 0.26). In a logistic regression analysis that adjusted for evaluation start time, the OR increased to 2.35, 95% CI = 1.002 – 5.53, p = 0.049. Also, including source (NEDICES vs. non-NEDICES) in the final model that also adjusted for evaluation start time, the OR increased to 2.65, 95% CI = 1.10 – 6.40, p = 0.03, indicating that accounting for this factor only enhanced the association.