Table 2.
Measure | Week | M (SD) | n | M (SD) | n | Change from Baseline | % Improvement | p | d (95% CI) | ||
---|---|---|---|---|---|---|---|---|---|---|---|
Structured Attention Control | Clinical Hypnosis | Structured Attention Control | Clinical Hypnosis | Structured Attention Control | Clinical Hypnosis | ||||||
HF FREQUENCY | Baseline | 75.21 (3.11) | 94 | 75.26 (2.82) | 93 | ||||||
6 week | 68.26 (3.10) | 90 | 27.19 (2.48) | 84 | −6.95 | −48.07 | 9.24 | 63.87 | p<.001 | 1.25 (38.84–47.85) | |
12 week | 62.32 (3.43) | 87 | 19.44 (1.96) | 78 | −12.89 | −55.82 | 17.13 | 74.16 | p<.001 | 1.27 (36.15–49.67) | |
| |||||||||||
HF-SCORE | Baseline | 22.94 (1.23) | 94 | 23.43 (1.02) | 93 | ||||||
6 week | 21.03 (1.15) | 90 | 6.71 (.79) | 84 | −1.91 | −16.72 | 8.32 | 71.36 | p<.001 | 1.23 (12.22–16.86) | |
12 week | 19.41 (1.36) | 87 | 4.61 (.56) | 78 | −3.53 | −18.83 | 15.38 | 80.32 | p<.001 | 1.21 (12.60–17.54) | |
| |||||||||||
HF MONITOR | Baseline | 8.85 (.75) | 88 | 10.41 (1.00) | 84 | ||||||
6 week | 9.48 (.87) | 78 | 6.15 (.81) | 68 | 0.63a | −4.26 | 7.11‡ | 40.92 | p<.001 | .52 (2.30–5.91) | |
12 week | 7.97 (.70) | 70 | 4.49 (.59) | 49 | −0.88 | −5.92 | 9.94 | 56.86 | p<.001 | .67 (2.00–5.46) | |
| |||||||||||
HFRDIS | Baseline | 5.75 (.24) | 94 | 5.87 (.23) | 93 | ||||||
6 week | 4.71 (.27) | 90 | 1.85 (.21) | 84 | −1.04 | −4.02 | 18.08 | 69.02 | p<.001 | 1.10 (2.37–3.47) | |
12 week | 4.43 (.28) | 87 | 1.05 (.20) | 78 | −1.32 | −4.82 | 22.96 | 82.11 | p<.001 | 1.22 (2.74–4.02) | |
| |||||||||||
SLEEP (PSQI) | Baseline | 11.89 (.48) | 94 | 11.69 (.56) | 93 | ||||||
6 week | 10.85 (.51) | 90 | 6.10 (.47) | 84 | −1.04 | −5.59 | 8.75 | 43.49 | p<.001 | 1.04 (3.65–5.84) | |
12 week | 10.66 (.55) | 87 | 5.42 (.47) | 78 | −1.23 | −6.27 | 10.34 | 53.63 | p<.001 | 1.07 (3.69–5.93) |
Abbreviations: HF, Hot Flash; HF-SCORE, Composite Score of Hot FlashFrequency X Hot Flash Severity; HF MONITOR, expert-rated hot flashes via skin conductance recording; HFRDIS, Hot Flash Related Daily Interference Scale, Mean score; HADS, Hospital Anxiety and Depression Scale -Anxiety subtotal; CESD, Center for Epidemiologic Studies -Depression Total Score; PSQI, Pittsburgh Sleep Quality Index -Global score; CI, 95% confidence interval. Effect size measures are Cohen’s d not adjusted for baseline and 95% confidence intervals for mean differences.
Indicates increased hot flashes