Table 2.

Anatomical definitions of skull landmarks collected from µCT images and shown on Fig 1. Skull regions: G- global skull; F- facial skeleton; B- cranial base; V- cranial vault; P- palate. These landmarks may be viewed at: http://www.getahead.psu.edu/LandmarkNewVersion/P0mouseskull_updated_applet.html

Landmark (Left, Right)	Anatomical definition	Skull region
1, 2	Most antero-medial point of the nasal bone	G, F
3, 4	Most postero-medial point of the nasal bone	G, F
5, 6	Intersection of frontal process of maxilla with frontal and lacrimal bones	G, F
7, 8	Intersection of malar with zygomatic process of maxilla, taken on maxilla	F
9, 10	Intersection of malar with zygomatic process of maxilla, taken on malar	F
11, 12	Intersection of zygoma with zygomatic process of temporal, taken on zygoma	G, F
13, 14	Most anterior point of the anterior palatine foramen	G, F
15, 16	Most posterior point of the anterior palatine foramen	G, F
17, 18	Most infero-lateral point of the premaxillary-maxillary suture, taken on premaxilla	G, F
19	Midline point on the premaxilla between the incisor and the nasal cavity just anterior of the incisive foramen, right side only	G, F
20	Most antero-superior point of the vomer	G, F
21	Most posterior point of the vomer	G, B
22	Most anterior point of the indentation in the center of the presphenoid	G, B
23, 24	Most anterior point on the anterior projection on the presphenoid	G, B
25, 26	Postero-medial point of the inferior portion of the left alisphenoid	G, B
27, 28	Most antero-lateral indentation at the posterior edge of the horizontal plate of the palatine bone	G, F
29, 30	Most posterior tip of the medial pterygoid process	G, B
31, 32	Most antero-lateral point on corner of the basioccipital at the basi occipital synchondrosis	G, B
33, 34	Most infero-lateral point on the squamous occipital	G, V
35	Mid-point on the posterior margin of the foramen magnum, taken on basioccipital	G, B
36	Mid-point on the anterior margin of the foramen magnum, taken on squamosal occipital	G, B
37, 38	Superior posterior point on the ectocranial surface of occipital lateralis on the foramen magnum	G, B
39, 40	Most posterior point on the posterior extension of the forming squamosal	G, V
41, 42	Most lateral intersection of the frontal and parietal bones, taken on the frontal	V
43, 44	Most lateral intersection of the frontal and parietal bones, taken on the parietal	V
49, 50	Most postero-medial point on the parietal	G, V
51	Most antero-medial point on the body of the sphenoid	G, B
P1, P2	Most anterolateral point on the posterior palatine plate	P
P3, P4	Most anteriomedial point on the posterior palatine plate	P
P5, P6	Most posteromedial point on the posterior palatine plate	P
P7, P8	Most posterolateral point on the posterior palatine plate	P