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. Author manuscript; available in PMC: 2013 Jan 27.
Published in final edited form as: Cancer. 2010 Jul 29;116(23):5461–5469. doi: 10.1002/cncr.25528

Table 1. Clinical, Surgical and Seizure Data.

Patient Age at DX (years) Tumor Location VF defect Seizure type AED Duration: seizure to surgery (years) Seizure control post surgery Extent of 1st resection Extent of 2nd resection Extent of 3rd resection Disease status at last follow-up
1 10.2 Temp QA SP-Sens Carbamazepine Levetiracetam 3.8 Resolved GTR NED
2 5.1 Front CP Carbamazepine 1 Resolved GTR NED
3 9.2 Temp Absencee Carbamazepine 0.3 Resolved GTR GTR NED
4 15 Par Normal NA Phenytoin 5g Resolved NTR SD
5 16.2 Temp GTC Phenytoin 2 Resolved GTR NED
6 9 Temp QAc Absencee Carbamazepine 1 Resolved GTR GTR GTR NED
7 13.7 Temp-Par-Occ QA CP Carbamazepine 0.4 Resolved NTR GTR NED
8 15.1 Temp-Par GTC Levetiracetam 0.0h Controlled NTR SD
9 5.5 Temp-Par HHd CP → GTC Carbamazepine 0.8 Resolved GTR NEDi
10a 6 Temp CP Zonisamidef Oxcarbazepine 1.5 Resolved STR STR SD
11b 11.6 Front Normal GTC Valproic acid Phenobarbital 1.8 Resolved BX GTR GTR NED

Abbreviations: AED, antiepilepsy drugs; BX, biopsy; CP, complex partial; Front, frontal; GTC, generalized tonic clonic; GTR, gross total resection; HH, homonymous hemianopia; NA, not available; NED, no evidence of disease; NTR, near-total resection; Occ, occipital; Par, parietal; QA, quadrantanopia; SD, stable disease; Sens, sensory; SP, simple parietal; STR, subtotal resection; Temp, temporal; VF, visual field.

a

The patient was seizure-free for 4 years, then seizures recurred and progressed during the next 8 years until a second resection was performed because of radiologic progression.

b

The patient underwent biopsy, and after 10 days, definite surgery. Five months later, the patient developed seizures, but the MRI was negative for a tumor. Approximately 4 years later, surgery was performed on the epileptic focus; no tumor was found.

c

The patient was blind in one eye because of congenital glaucoma and had QA in the other eye.

d

The visual field test used was a confrontational test administered by a neurologist.

e

The diagnosis of absence seizure was based on retrospective history from family and patients that was taken after the surgery; no EEG was performed to confirm.

f

The patient failed 11 different AED until the second surgery, where he needed only 2 AED after second surgery for 2 years and was able to stop AED without recurrence of seizures.

g

The patient had CT shortly after surgery and it showed a a mass, but the family deferred surgery for 5 years.

h

The duration from seizure to surgery in this patient was only 2 weeks.

i

The patient died from a cause not related to his disease after last contact.