Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Reagents and conditions: (a) H2SO4, acetone, room temperature, 1.5 h, ~ 90%; (b) (i) LDA, THF, −78 °C, 2 h; (ii) EtOC(O)CN, THF, −78 °C, 50 min, 70–75%; (c) (i) NaOH/THF, room temperature, 3 h; (ii) Dowex 50WX8-100 (H+), H2O, 45 °C, 90–100%.
