Table 5.
Factors Independently Associated With Incident Prediabetes and Type 2 Diabetes in Obese Adults
| Absolute Risk Increase, % | Odds Ratio (95% CI) | P Value | χ2 Value | |
|---|---|---|---|---|
| Incident Type 2 Diabetes in Participants Without Diabetes at Baseline | ||||
| Fasting blood glucose, per 1 SD (1.1 mg/dL)a | 5.7 | 1.88 (1.38–2.56) | <.001 | 16.1 |
|
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| Family history of diabetes | 6.8 | 2.32 (1.25–4.29) | .008 | 7.1 |
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| Systolic blood pressure, per 10 mm Hg | 2.0 | 1.26 (1.07–1.48) | .006 | 7.6 |
|
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| Visceral fat, per 1 SD (1.4 kg)a | 8.8 | 2.42 (1.59–3.68) | <.001 | 17.0 |
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| ||||
| Fructosamine, per 1 SD (1.1 μmol/L)a | 6.1 | 1.95 (1.43–2.67) | <.001 | 17.7 |
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| ||||
| Weight gain, per 1 kg | 0.5 | 1.06 (1.02–1.10) | .002 | 9.8 |
|
| ||||
| Incident Prediabetes or Type 2 Diabetes in Participants With Normal Fasting Glucose Values at Baseline | ||||
| Fasting blood glucose, per 1 SD (1.1 mg/dL)a | 9.4 | 1.66 (1.29–2.12) | <.001 | 16.0 |
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| ||||
| Nonwhite race | 9.7 | 1.77 (1.08–2.91) | .02 | 5.2 |
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| Family history of diabetes | 8.9 | 1.60 (1.05–2.44) | .03 | 4.8 |
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| ||||
| Age, per 10 y | 7.2 | 1.48 (1.17–1.86) | .001 | 10.9 |
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| Visceral fat, per 1 SD (1.4 kg)a | 7.3 | 1.48 (1.17–1.88) | .001 | 10.8 |
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| Fructosamine, per 1 SD (1.1 μmol/L)a | 6.5 | 1.42 (1.14–1.75) | .001 | 10.2 |
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| ||||
| Insulin, per 1 SD (1.7 μU/mL)a | 5.7 | 1.34 (1.06–1.70) | .01 | 6.1 |
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| ||||
| Weight gain, per 1 kg | 1.2 | 1.08 (1.05–1.10) | <.001 | 40.9 |
a
Incremental change equivalent to a 1-SD difference in the log-transformed continuous variable.